US patent granted for selected drugs 

US patent granted for theranostic assay platform

Australian patent granted for theranostic assay platform

Kick-off day for new EU Project FORCE REPAIR: Innovating Chronic Wound Treatment

As a member of a multi-disciplinary and multi-national consortium, Akribes was granted funding by the European Union for the Horizon Europe project entitled FORCE REPAIR, the acronym for “smart and multiFunctional 3D printable prO-Regenerative biologiCal matrix modulating mEchanotRansduction as advancEd theraPy to treAt skIn chRonic wounds.”
The goal of this ambitious project is to improve chronic wound treatment with customized wound dressings by 3D-printing of functionalized bio-inks to relieve skin tension, fight infection, reduce inflammation and support regeneration of healthy tissue.

Please see the FORCE_REPAIR_Press release for more details, and follow the project on the website https://forecepair-wounds.eu and the FORCE REPAIR LinkedIn account.

Japanese patent granted for theranostic assay platform

Chinese patent granted for theranostic assay platform

TÜV Süd granted an ISO 13485:2016 Certificate for the Akribes Quality Management System (QMS)

The QMS at Akribes complies with the DIN EN ISO13485:2016 standard for medical devices. The certificate covers the scope of “Design and Development, Production and Sales of lab-on-a-chip devices and IVD software for diagnostics and therapy recommendation for chronic/non-healing wounds.

EU patent granted for selected drugs

EU patent granted for drug combinations

EU patent granted for theranostic assay platform

Meet us at the 34^th Conference of the European Wound Management Association, EWMA 2024, in London, United Kingdom.

Kirketerp-Møller K, Doerfler P, Schoefmann N, Wolff-Winiski B, Niazi O, Pless V, Karlsmark T and Ågren MS. (2022)
Biomarkers of skin graft healing in venous leg ulcers.
Acta Derm Venereol. 2022;102:adv00749. doi: 10.2340/actadv.v102.201. 

Cabral G, Doerfler P, Schoefmann N, Stuetz A, Wolff-Winiski B (2023)
The early transcriptional response of fibroblasts to non-healing wound exudates reveals roles for inflammation and unfolded protein response in the pathology of chronic wounds.
Poster at the 5^th Inflammatory Skin Disease Summit (ISDS), Nov. 15-18, 2023, Vienna, Austria

Schoefmann N, Schwarz A, Kotzbeck P, Wolff-Winiski B (2023)
Effect of chronic wound exudates on human adipocytes.
Poster at the European Wound Management Association (EWMA) meeting, May. 3 - 5, 2023 in Milan, Italy

Wolff-Winiski B, Schoefmann N, Doerfler P, Cabral G, Stuetz A. (2022)
Identification of the selective glucocorticoid receptor agonist Mapracorat as potential new drug for chronic wound therapy.
51st Annual ESDR Meeting, Sept. 28 – Oct. 1 2022, Amsterdam, The Netherlands
J Invest Dermatol 142 (12) Suppl S286 Abstr. No 610

Wolff-Winiski B, Doerfler P, Schoefmann N, Cabral G, Stuetz A. (2022)
Development of an assay platform for personalized treatment of chronic wounds.
51st Annual ESDR Meeting, Sept. 28 – Oct. 1 2022, Amsterdam, The Netherlands
J Invest Dermatol 142 (12) Suppl S286 Abstr. No 602

Schoefmann N, Doerfler P, Cabral G, Stuetz A, Wolff-Winiski B (2022)
Characterization of poly(ADP-ribose) polymerase (PARP) inhibitors as potential new drugs for chronic wound therapy.
EWMA-Journées Cicatrisations Meeting, May 23-25, 2022, Paris, France
J Wound Management 23 (1) S62 Abstr. No EP194

Cabral G, Doerfler P, Schoefmann N, Stuetz A, Wolff-Winiski B (2021)
Exposure of human dermal fibroblasts to chronic wound exudates triggers pro-inflammatory and anti-proliferative transcriptional changes.
Poster at the European Wound Management Association (EWMA), 26-27 October, 2021

Doerfler P, Stuetz A, Wolff-Winiski B (2021)
Development of a novel keratinocyte migration assay as a model for re-epithelialization of chronic wounds.
Poster at the European Wound Management Association (EWMA), 26-27 October, 2021

Schoefmann N, Doerfler P, Berli M, Binder B, Botter SM, Hafner J, Hanfstingl K, Hoetzenecker W, Holzer JCJ, Kamolz LP, Mica L, Michelitsch B, Nischwitz S, Popovits M, Restivo G, Stuetz A, Wolff-Winiski B (2020)
Development of an ex vivo assay to differentiate between non-healing and healing wounds based on wound swabs.
Poster at the European Wound Management Association (EWMA), 18-20 November, 2020

Doerfler P, Schoefmann N, Stuetz A, Wolff-Winiski B (2020)
Screening of Wound Healing Therapeutics with an ex vivo Assay Platform using Wound Exudates from Individual Patients.
Poster at the European Academy of Dermatology and Venereology (EADV), 28-31 October, 2020

Doerfler P, Schoefmann N, Berli M, Bauer W, Botter S, Frustaci D, Goerge T, Luger T, Mica L, Popovits M, Rappersberger K, Stingl G, Stockinger T, Stuetz A, Wolff-Winiski B (2020)
On the Way to Personalized Treatment of Chronic Wounds.
Poster at the European Academy of Dermatology and Venereology (EADV), 28-31 October, 2020

Doerfler P, Bauer W, Goerge T, Luger T, Rappersberger K, Stingl G, Schoefmann N, Stockinger T, Stuetz A, Wolff-Winiski B (2019)
Effect of human wound exudates obtained by vacuum therapy on fibroblast proliferation and extracellular matrix formation.
EWMA 2019, 5-7 June, 2019, Gothenburg, Sweden

Doerfler P, Stuetz A, Wolff-Winiski B (2018)
Effect of exogenous platelet-derived growth factor on the proliferation of human fibroblasts in the presence of human wound exudates.
International Investigative Dermatology Meeting, May 16-19, 2018, Orlando, USA
J Invest Dermatol 138, Suppl 1:S242, Abstr. No 1428

Doerfler P, Bauer W, Goerge T, Luger T, Rappersberger K, Stingl G, Stockinger T, Stuetz A, Wolff-Winiski B (2017)
Comparative analysis of cytokines, proteases and growth factors in human wound exudates obtained by vacuum therapy.
47th European Society Dermatological Research Meeting, 2017, Salzburg, Austria
J Invest Dermatol 137, Suppl 1:S312, Abstr. No 694